Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1989 May;57(5):1629-31.
doi: 10.1128/iai.57.5.1629-1631.1989.

Comparison of the genomes of pathogenic treponemes of human and animal origin

P de Wergifosse  1 , M M Coene
Affiliations

Comparison of the genomes of pathogenic treponemes of human and animal origin

P de Wergifosse et al. Infect Immun. 1989 May.

Abstract

The aim of this study was to compare the genomes of two strains of intestinal treponemes, which were isolated from patients suffering from intestinal disorders, with that of Treponema hyodysenteriae, the known etiological agent of swine dysentery (bloody scours). The guanine-plus-cytosine contents of the three DNAs were found to be 28.5 to 30.0%. DNA-DNA hybridization in liquid phase indicated a high degree of homology (56 to 95%) among the human strains and with T. hyodysenteriae. One of the human strains in particular displayed a very high homology (91 to 95%) with T. hyodysenteriae. The overall conclusion is that treponemal strains pathogenic for humans and animals are clustered within the same species (we propose T. hyodysenteriae), which suggests the possibility of exchange of pathogenic microorganisms between domestic animals and humans.

PubMed Disclaimer

References

    1. Eur J Epidemiol. 1987 Jun;3(2):187-95 - PubMed
    1. J Mol Biol. 1962 Jun;4:430-43 - PubMed
    1. Can Vet J. 1962 Aug;3(8):228-37 - PubMed
    1. Vet Med Small Anim Clin. 1972 Jan;67(1):61-4 - PubMed
    1. Eur J Biochem. 1985 Aug 1;150(3):475-9 - PubMed

LinkOut - more resources