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Comment
. 2016 Apr 14;127(15):1842-3.
doi: 10.1182/blood-2016-03-701680.

How to avoid being eaten: a lymphoma's defense

Nora Heisterkamp  1
Affiliations
Comment

How to avoid being eaten: a lymphoma's defense

Nora Heisterkamp. Blood. .

Abstract

In this issue of Blood, Lykken et al used an immunocompetent mouse model of B-cell lymphoma to discover an interesting new way in which these malignant cells can avoid being killed in the presence of anti-CD20 antibodies.

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Conflict of interest statement

Conflict-of-interest disclosure: The author declares no competing financial interests.

Figures

None
Flow cytometry analysis of phagocytosis by F4/80-positive murine peritoneal macrophages cocultured with BL3750 lymphoma cells previously incubated with anti-CD20 mAb shows addition of Gal-1 inhibits engulfment as evidenced by decreased percentage of events in the upper right quadrant. Ctrl, control; rGal-1, recombinant Gal-1. See the complete Figure 6 in the article by Lykken et al that begins on page 1886.
See this image and copyright information in PMC

Comment on

References

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