siRNA Therapeutics for Primary Hyperoxaluria: A Beginning
- PMID: 27081720
- PMCID: PMC4886951
- DOI: 10.1038/mt.2016.50
siRNA Therapeutics for Primary Hyperoxaluria: A Beginning
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Comment on
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Glycolate Oxidase Is a Safe and Efficient Target for Substrate Reduction Therapy in a Mouse Model of Primary Hyperoxaluria Type I.Mol Ther. 2016 Apr;24(4):719-25. doi: 10.1038/mt.2015.224. Epub 2015 Dec 22. Mol Ther. 2016. PMID: 26689264 Free PMC article.
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Inhibition of Glycolate Oxidase With Dicer-substrate siRNA Reduces Calcium Oxalate Deposition in a Mouse Model of Primary Hyperoxaluria Type 1.Mol Ther. 2016 Apr;24(4):770-8. doi: 10.1038/mt.2016.4. Epub 2016 Jan 13. Mol Ther. 2016. PMID: 26758691 Free PMC article.
References
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- Bobbin, ML and Rossi, JJ (2016). RNA interference (RNAi)-based therapeutics: delivering on the promise? Annu Rev Pharmacol Toxicol 56: 103–122. - PubMed
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- Coelho T, Adams, D, Silva, A, Lozeron, P, Hawkins, PN, Mant, T et al. (2013). Safety and efficacy of RNAi therapy for transthyretin amyloidosis. N Engl J Med 369: 819–829. - PubMed
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- Cochat, P and Rumsby, G (2013). Primary hyperoxaluria. N Engl J Med 369: 649–658. - PubMed
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