Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2017 Jan-Mar;10(1):3-4.
doi: 10.1016/j.optom.2016.03.002. Epub 2016 Apr 13.

Presence of melatonin in human tears

Affiliations

Presence of melatonin in human tears

Gonzalo Carracedo et al. J Optom. 2017 Jan-Mar.
No abstract available

PubMed Disclaimer

Figures

Figure 1
Figure 1
Melatonin amount in human tears at different moments of the day. The morning (8 h) concentrations were (0.81[0.60, 0.99] μM (10–3 mol/L)), afternoon (15 h) concentrations were (0.94 [0.69, 1.40] μM) and night (24 h) concentrations were (1.67 [1.18, 3.25] μM) (medians and quartiles). Differences discussed in the text.

References

    1. Stehle J.H., Saade A., Rawashdeh O. A survey of molecular details in the human pineal gland in the light of phylogeny, structure, function and chronobiological diseases. J Pineal Res. 2011;51:17–43. - PubMed
    1. Claustrat B., Leston J. Melatonin: physiological effects in humans. Neuro-Chirurgie. 2015;61:77–84. - PubMed
    1. Wiechmann A.F., Summers J.A. Circadian rhythms in the eye: the physiological significance of melatonin receptors in ocular tissues. Prog Retin Eye Res. 2008;27:137–160. - PubMed
    1. Alarma-Estrany P., Pintor J. Melatonin receptors in the eye: location, second messengers and role in ocular physiology. Pharmacol Ther. 2007;113:507–522. - PubMed
    1. Crooke A., Guzman-Aranguez A., Mediero A. Effect of melatonin and analogues on corneal wound healing: involvement of Mt(2) melatonin receptor. Curr Eye Res. 2015;40:56–65. - PubMed