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Review
. 2016 Jul;23(5):364-72.
doi: 10.1111/micc.12281.

Nailfold Capillaroscopy and Clinical Applications in Systemic Sclerosis

Vanessa Smith  1   2 , Kristof Thevissen  2 , Amelia C Trombetta  3 , Carmen Pizzorni  3 , Barbara Ruaro  3 , Yves Piette  2 , Sabrina Paolino  3 , Filip De Keyser  1   2 , Alberto Sulli  3 , Karin Melsens  1 , Maurizio Cutolo  3 ; EULAR Study Group on Microcirculation in Rheumatic Diseases
Affiliations
Review

Nailfold Capillaroscopy and Clinical Applications in Systemic Sclerosis

Vanessa Smith et al. Microcirculation. 2016 Jul.

Abstract

Capillary microscopy is a safe and non-invasive tool to evaluate the morphology of the microcirculation typically affected in SSc. Next to being paramount for the "(very) early" diagnosis of SSc eyes are also geared toward capillaroscopy with the aim to be able to use it as a biomarker, especially in the prediction of future occurrence of DU. The following review will explain what capillary microscopy is and will focus additionally on studies evaluating the association between capillaroscopy and DU.

Keywords: Raynaud's phenomenon; biomarker; capillaroscopy; digital trophic lesions; qualitative/quantitative assessment; systemic sclerosis.

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