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Review
. 2016 Apr;4(2):165-71.
doi: 10.1177/2050640615597835. Epub 2015 Aug 21.

Crohn's disease and skin

A G Gravina  1 , A Federico  1 , E Ruocco  2 , A Lo Schiavo  2 , F Romano  2 , A Miranda  1 , D Sgambato  1 , M Dallio  1 , V Ruocco  2 , C Loguercio  1 , M Romano  1
Affiliations
Review

Crohn's disease and skin

A G Gravina et al. United European Gastroenterol J. 2016 Apr.

Abstract

Crohn's disease is a chronic inflammatory bowel disease potentially involving any segment of the gastrointestinal tract. Extra-intestinal manifestations may occur in 6%-40% of patients, and disorders of the skin are among the most common. This manuscript will review skin manifestations associated to Crohn's disease, with a particular focus on lesions associated to anti-tumour necrosis factor therapy.

Keywords: Crohn’s disease; anti-tumour necrosis factor-alpha; dermatologic manifestation; inflammatory bowel disease.

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Figures

Figure 1.
Figure 1.
Pyoderma gangrenosum of the extensor aspect of the leg in a Crohn's disease patient.
Figure 2.
Figure 2.
Palmar (a) and perianal (b) psoriasis in a Crohn's disease patient on anti-TNF therapy.
Figure 3.
Figure 3.
Bowen's disease (i.e. squamous cell carcinoma in situ) on the extensor aspect of the arm in a Crohn's disease patient on anti-TNF therapy.
See this image and copyright information in PMC

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