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. 2016:2016:7030791.
doi: 10.1155/2016/7030791. Epub 2016 Mar 21.

Microperimetric Assessment after Epiretinal Membrane Surgery: 4-Year Follow-Up

Affiliations

Microperimetric Assessment after Epiretinal Membrane Surgery: 4-Year Follow-Up

Marco Dal Vecchio et al. J Ophthalmol. 2016.

Abstract

Purpose. To investigate retinal function using microperimetry in patients affected by idiopathic epiretinal membrane (iERM) and cataract who underwent combined surgery: 4-year follow-up. Design. Prospective, interventional case series. Methods. 30 eyes of 30 consecutive patients with iERM and age-related cataract underwent 25-gauge vitrectomy and cataract surgery. At baseline, 90 and 180 days, and 1 and 4 years, we examined retinal mean sensitivity (MS), retinal mean defect (MD), fixation stability, and frequency of microscotomas using MP1 microperimetry. Best-corrected visual acuity (BCVA) and central retinal thickness (CRT) using a spectral domain optical coherence tomography (SD-OCT) were also performed. Results. All patients completed 1-year follow-up, while 23 patients reached last follow-up. Baseline MS and MD (10.48 ± 4.17 and -9.18 ± 4.40 dB) significantly changed at one year (12.33 ± 3.66 and -7.49 ± 3.31 dB, p < 0.01), at four years (14.18 ± 3.46 and -4.66 ± 2.85, p < 0.01), and between one and four years (p < 0.01) after surgery. Compared to baseline, CRT and BCVA significantly changed at one year and remained stable at four years. No variations were observed in fixation stability and frequency of microscotomas compared to baseline. Conclusions. Long-term follow-up using microperimetry seems useful to evaluate patients after iERM surgery: retinal sensitivity changes even when BCVA and CRT remain stable.

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Figures

Figure 1
Figure 1
Mean sensitivity and mean defect values before and after surgery (mean ± standard deviation).

References

    1. Mitchell P., Smith W., Chey T., Wang J. J., Chang A. Prevalence and associations of epiretinal membranes. The Blue Mountains Eye Study, Australia. Ophthalmology. 1997;104(6):1033–1044. doi: 10.1016/s0161-6420(97)30190-0. - DOI - PubMed
    1. Bu S.-C., Kuijer R., Li X.-R., Hooymans J. M. M., Los L. I. Idiopathic epiretinal membrane. Retina. 2014;34(12):2317–2335. doi: 10.1097/IAE.0000000000000349. - DOI - PubMed
    1. Rizzo S., Genovesi-Ebert F., Murri S., et al. 25-Gauge, sutureless vitrectomy and standard 20-gauge pars plana vitrectomy in idiopathic epiretinal membrane surgery: a comparative pilot study. Graefe's Archive for Clinical and Experimental Ophthalmology. 2006;244(4):472–479. doi: 10.1007/s00417-005-0173-6. - DOI - PubMed
    1. Ripandelli G., Scarinci F., Piaggi P., et al. Macular pucker: to peel or not to peel the internal limiting membrane? A microperimetric response. Retina. 2015;35(3):498–507. doi: 10.1097/iae.0000000000000330. - DOI - PubMed
    1. Liu H., Zuo S., Ding C., Dai X., Zhu X. Comparison of the effectiveness of pars plana vitrectomy with and without internal limiting membrane peeling for idiopathic retinal membrane removal: a meta-analysis. Journal of Ophthalmology. 2015;2015:10. doi: 10.1155/2015/974568.974568 - DOI - PMC - PubMed