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. 2016 Apr;34(2):81-5.
doi: 10.2337/diaclin.34.2.81.

Lixisenatide: A New Member of the Glucagon-Like Peptide 1 Receptor Agonist Class of Incretin Therapies

Charles F Shaefer Jr  1
Affiliations

Lixisenatide: A New Member of the Glucagon-Like Peptide 1 Receptor Agonist Class of Incretin Therapies

Charles F Shaefer Jr. Clin Diabetes. 2016 Apr.

Abstract

In Brief In the past decade, various incretin-based therapies have emerged in clinical practice. These drugs, including dipeptidyl peptidase-4 inhibitors and glucagon-like peptide 1 (GLP-1) receptor agonists lower A1C with weight-neutral or weight-lowering effects and a relatively lower risk of hypoglycemia. This article provides a review of lixisenatide, a once-daily GLP-1 receptor agonist for the treatment of type 2 diabetes.

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References

    1. Bayless WM, Starling EH. Mechanisms of pancreatic secretion. J Physiol (Lond) 1902;28:234–1902 - PMC - PubMed
    1. Moore B. On the treatment of diabetus mellitus by acid extract of duodenal mucous membrane. Biochem J 1906;1:28–38 - PMC - PubMed
    1. Zunz E, LaBarre J. Contributions a l’etude des variations physiologiques entre des la secretion intune du pancreas: relations entre les secretions externe et interne du pancreas. Arch Int Physiol Biochem 1929;31:20–44 [in French]
    1. LaBarre J, Still EU. Studies on the physiology of secretin. Am J Physiol 1930;91:649–653
    1. Loew ER, Grey ES, Ivy AC. Is a duodenal hormone involved in carbohydrate metabolism? Am J Physiol 1940;129:659–663