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. 2016 Apr;21(2):145-50.
doi: 10.17712/nsj.2016.2.20150783.

Planimetry investigation of the corpus callosum in temporal lobe epilepsy patients

Veli Caglar  1 , Selen I Alp, Berrin T Demir, Umit Sener, Oguz A Ozen, Recep Alp
Affiliations

Planimetry investigation of the corpus callosum in temporal lobe epilepsy patients

Veli Caglar et al. Neurosciences (Riyadh). 2016 Apr.

Abstract

Objective: To evaluate the effects of temporal lobe epilepsy (TLE) on corpus callosum (CC) morphometry in patients with TLE.

Methods: This retrospective study was conducted at the Faculty of Medicine, Tekirdag Namik Kemal University, Tekirdag, Turkey between November 2010 and December 2013. The epileptic syndrome diagnosis was based on International League Against Epilepsy criteria, and this study was conducted on the MRIs of 25 epilepsy patients and 25 control subjects. We classified the patients according to their duration of epilepsy: <10 and >/=10 years. The projection area length (PAL) of the CC was also estimated. Total brain volumes (TBV) were measured on CT images.

Results: The mean values of TBV for patients with TLE and the control group were not statistically different, but the CC PAL values were statistically different. The mean CC PAL values of under and over 25 years of age in patients with TLE were statistically different. The mean values of TBV of under and over 10 years duration of TLE were small statistically, but the CC PAL values were statistically different.

Conclusion: The results indicate a clear influence of TLE on the structure of the CC rather than TBV.

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Figures

Figure 1
Figure 1
Measurements of the planimetry technique for the assessment of the projection areas length of the corpus callosum using ImageJ software. a) Indicates is the length of corpus callosum (L), b) the surface area of the corpus callosum, A - indicates the surface area of the corpus callosum, and L - is the length of corpus callosum.
See this image and copyright information in PMC

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