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Case Reports
. 2016 Apr-Jun;31(2):138-40.
doi: 10.4103/0972-3919.178302.

FDG PET/CT findings in a clinically diagnosed case of childhood autism

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Case Reports

FDG PET/CT findings in a clinically diagnosed case of childhood autism

Ashmi S Manglunia et al. Indian J Nucl Med. 2016 Apr-Jun.

Abstract

Autism is a neurodevelopmental disorder with multifactorial etiology and varied presentation, in which early diagnosis is crucial to the implementation of early treatment. A 6-year-old child clinically diagnosed with autism, and a normal magnetic resonance imaging underwent dedicated 18F-fluorodeoxyglucose brain positron emission tomography (PET) as an ancillary investigation. PET image showed diffuse bilateral temporal hypometabolism. Although PET imaging is currently not indicated in the evaluation of autism, characteristic imaging patterns on PET can provide corroborative information and increase the diagnostic confidence for the same.

Keywords: Autism; brain positron emission tomography; functional imaging.

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Figures

Figure 1
Figure 1
(a) Transaxial images of brain PET show diffuse hypometabolism in bilateral temporal lobes (marked by red arrows). Rest of the brain parenchyma shows physiological tracer distribution. (b) Transaxial image in grayscale showing bilateral temporal hypometabolism as marked
Figure 2
Figure 2
Coronal images of brain positron emission tomography from anterior to posterior direction showing low uptake in bilateral temporal lobes
Figure 3
Figure 3
Transaxial section of brain positron emission tomography image with corresponding color scale, showing bilateral hypometabolism

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