Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2016 Apr;20(2):94-8.
doi: 10.1055/s-0036-1579743. Epub 2016 Mar 9.

Obliquity of the Stapes in Otosclerosis: A New Radiological Sign

Affiliations

Obliquity of the Stapes in Otosclerosis: A New Radiological Sign

Veluswamy Anand et al. Int Arch Otorhinolaryngol. 2016 Apr.

Abstract

Introduction Observing the obliquity of stapes by closely scrutinizing the HRCT temporal bone in otosclerosis revealed a reliable and consistent finding. This finding can add to the existing radiological criteria in diagnosis of otosclerosis. Objective The objective of this study is to establish the obliquity of stapes in otosclerosis by radiological measurements using HRCT temporal bone by comparing: (a) the distance between the horizontal (tympanic) segment of facial nerve and stapes head in otosclerotic ears (study group) with non-otosclerotic ears (control group); and (b) the angle subtended by stapes with promontory in the study and control groups. Methods This is a prospective study performed after the institutional Ethics Committee clearance (IEC 3/2013). Results An increased mean distance between the horizontal segment of facial nerve and stapes head in otosclerotic patients (i.e., 2.49mm +/- 0.24mm SD), when compared with the non-otosclerotic patients (i.e., 1.46mm +/- 0.16mm SD) is noted. There is a change in angle (i.e., 64.550 +/- 7.190 SD) subtended by the stapes toward the promontory in otosclerotic ears when compared with that of controls (i.e., 99.700 +/- 40 SD). We applied the Mann-Whitney U non-parametric test and considered p value of < 0.0001 highly significant. Conclusions Obliquity of stapes in otosclerosis referred to as a "Pisa" sign by the senior author has diagnostic value as a new radiological sign in imaging of otosclerosis. This obliquity explains the torsional effect of otosclerosis on the ossicular chain. The findings correlate with late complications and failures in stapes surgery.

Keywords: obliquity; otosclerosis; stapes; temporal bone.

PubMed Disclaimer

Conflict of interest statement

Financial Disclosure All financial and material support by MCV Memorial ENT Trust Hospital. The authors declare no conflict of interest.

Figures

Fig. 1
Fig. 1
Illustration showing the increase in length from facial nerve to stapes head due to obliquity of stapes in otosclerosis (dotted line).
Fig. 2
Fig. 2
Illustration showing change in angle due to obliquity of stapes in otosclerosis (dotted line).
Fig. 3
Fig. 3
HRCT Temporal bone coronal image showing length and angle measured in Otosclerotic patient.
Fig. 4
Fig. 4
HRCT Temporal bone coronal image showing angle measured in otosclerotic patient.
Fig. 5
Fig. 5
HRCT Temporal bone length measured in non-otosclerotic patient.
Fig. 6
Fig. 6
HRCT Temporal bone showing angle measured in non-otosclerotic patient.
Fig. 7
Fig. 7
Graph showing (Scatter dot) HRCT length between stapes head and facial nerve in otosclerosis and non-otosclerosis patients.
Fig. 8
Fig. 8
Graph showing (Scatter dot) angle subtended by stapes with promontory in otosclerosis and non-otosclerosis patients.

References

    1. Politzer A. Uber primare Erkrankung der Knocheren Labyrinth-Kapsel. Johrenheilk. 1894;25:309–327.
    1. Anson B J, Cauldwell E W, Bast T H. The fissula ante fenestram of the human otic capsule; developmental and normal adult structure. Ann Otol Rhinol Laryngol. 1947;56(4):957–985. - PubMed
    1. Bast T H. Development of otic capsule. Residual cartilages and defective ossification and their relation to otosclerotic foci. Arch Otolaryngol. 1940;32:771–782.
    1. Anson B J, Cauldwell E W, Bast T H. The fissula ante fenestram of the human otic capsule; aberrant form and contents. Ann Otol Rhinol Laryngol. 1948;57(1):103–128. - PubMed
    1. Swartz D J, Loevener A L. New York, USA: Thieme; 2009. Imaging of the Temporal bone. 4th ed.