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. 1989 Jan-Feb;13(1):25-6.
doi: 10.1093/jat/13.1.25.

Determination of ethylene glycol in postmortem blood by capillary gas chromatography

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Determination of ethylene glycol in postmortem blood by capillary gas chromatography

J A Jonsson et al. J Anal Toxicol. 1989 Jan-Feb.

Abstract

A simple procedure for the determination of ethylene glycol in blood by capillary gas chromatography was developed. The proteins are precipitated by the addition of perchloric acid which includes the internal standard 1,2-butanediol. The extract is neutralized and the solution is directly injected. The assay is linear and the precision, expressed as coefficient of variation, is 4-11% (within run). The detection limit is about 0.05 g/L. The method also seems applicable for the determination of ethylene glycol in urine.

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