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. 1989 Feb;9(2):851-3.
doi: 10.1128/mcb.9.2.851-853.1989.

Induction of beta-polymerase mRNA by DNA-damaging agents in Chinese hamster ovary cells

A J Fornace Jr  1 , B Zmudzka, M C Hollander, S H Wilson
Affiliations

Induction of beta-polymerase mRNA by DNA-damaging agents in Chinese hamster ovary cells

A J Fornace Jr et al. Mol Cell Biol. 1989 Feb.

Abstract

Only a few of the genes involved in DNA repair in mammalian cells have been isolated, and induction of a DNA repair gene in response to DNA damage has not yet been established. DNA polymerase beta (beta-polymerase) appears to have a synthetic role in DNA repair after certain types of DNA damage. Here we show that the level of beta-polymerase mRNA is increased in CHO cells after treatment with several DNA-damaging agents.

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