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Comment
. 2016 Apr 21;127(16):1947-8.
doi: 10.1182/blood-2016-01-692087.

When kissing (disease) counts

Affiliations
Comment

When kissing (disease) counts

Katrien Van Roosbroeck et al. Blood. .

Abstract

In this issue of Blood, Kanakry et al analyzed Epstein-Barr virus (EBV) DNA expression in peripheral blood cellular compartments from 2146 patients with various malignancies and found that cell-free plasma EBV DNA was a better marker of EBV+ disease than EBV DNA from peripheral blood mononuclear cells (PBMCs).

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Conflict of interest statement

Conflict-of interest disclosure: The authors declare no competing financial interests.

Figures

None
EBV DNA in plasma had better sensitivity (A) and specificity (B) than PBMCs in distinguishing between patients with active, systemic EBV+ disease and patients that did not have prior, current, or subsequent history of EBV+ disease. See Figure 2B-C in the article by Kanakry et al that begins on page 2007.

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References

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