Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2016 Mar 1;51(1):52-6.
doi: 10.5152/TurkPediatriArs.2016.1548. eCollection 2016 Mar.

The association of consumptive hypothyroidism secondary to hepatic hemangioma and severe heart failure in infancy

Suna Emir  1 , Filiz Ekici  2 , Mehmet Alper İkiz  1 , Sadi Vidinlisan  3
Affiliations
Case Reports

The association of consumptive hypothyroidism secondary to hepatic hemangioma and severe heart failure in infancy

Suna Emir et al. Turk Pediatri Ars. .

Abstract

Although hemangiomas are the most common vascular tumors of the liver in infancy, data regarding hypothyroidism and heart failure related to hepatic hemangiomas are limited. Here, we present a 15- day -old girl who presented with prolonged jaundice at the age of 15 days. Because her TSH level was found to be 74 μIU/mL, she was initially diagnosed with congenital hypothyroidism and L-Thyroxine replacement therapy was initiated. On follow-up examination performed two months later, it was observed that her TSH level was not suppressed and a mass was noticed in the right upper abdomen on physical examination. Abdominal ultrasonography revealed multiple masses with sizes of about 3-3,5 cm covering the whole liver. When evaluated with clinical and radiological appearance, oral methylprednisolone at a dose of 5 mg/kg/day and propranolol at a dose of 2 mg/kg were initiated with a diagnosis of hepatic hemagioma/hemangioendothelioma. Consumptive hypothyroidism due to hepatic hemangioma and congestive heart failure were considered in the patient who had findings of heart failure. The dose of L-Thyroxine was increased 2-fold. The patient received intensive care treatment for severe heart failure. Because his findings resolved, he was started to be followed up with propranolol, steroid and L-Thyroxine treatment.

Keywords: Hypothyroidism; heart failure; hepatic hemangioma; infant.

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
Abdominal magnetic resonance imaging: hyperintense masses covering the liver with markedly increased vascularization on T2-weighted imaging
See this image and copyright information in PMC

References

    1. Nazir Z, Pervez S. Malignant vascular tumors of liver in neonates. J Pediatr Surg. 2006;41:49–51. http://dx.doi.org/10.1016/j.jpedsurg.2005.10.078. - DOI - PubMed
    1. Christison-Lagay ER, Burrows PE, Alomari A, et al. Hepatic hemangiomas: subtype classification and development of a clinical practice algorithm and registry. J Pediatr Surg. 2007;42:62–8. http://dx.doi.org/10.1016/j.jpedsurg.2006.09.041. - DOI - PubMed
    1. Schweinitz D. Neonatal liver tunors. Semin Neonotogy. 2003;8:403–10. http://dx.doi.org/10.1016/S1084-2756(03)00092-7. - DOI - PubMed
    1. Bosemani T, Puttgen KB, Huisman TA, Tekes A. Multifocal infantile hepatic hemangiomas- imaging strategy and response to treatment after propronolol and steroids including review of the literature. Eur J Pediatr. 2012;171:1023–8. http://dx.doi.org/10.1007/s00431-011-1671-7. - DOI - PubMed
    1. Zhang Z, Chen HJ, Yang WJ, et al. Infantile hepatic hemangioendothelioma: a clinicopathologic study in a Chinese population. World J Gastroenterol. 2010;16:4549–57. http://dx.doi.org/10.3748/wjg.v16.i36.4549. - DOI - PMC - PubMed

Publication types

LinkOut - more resources