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. 2016 Mar;48(1):20-30.
doi: 10.3947/ic.2016.48.1.20. Epub 2016 Mar 31.

Travel Pattern and Prescription Analysis at a Single Travel Clinic Specialized for Yellow Fever Vaccination in South Korea

Affiliations

Travel Pattern and Prescription Analysis at a Single Travel Clinic Specialized for Yellow Fever Vaccination in South Korea

Bum Sik Chin et al. Infect Chemother. 2016 Mar.

Abstract

Background: Travel-related risks for infectious diseases vary depending on travel patterns such as purpose, destination, and duration. In this study, we describe the patterns of travel and prescription of vaccines as well as malaria prophylaxis medication (MPM) at a travel clinic in South Korea to identify the gaps to fill for the optimization of pre-travel consultation.

Materials and methods: A cohort of travel clinic visitors in 2011 was constructed and early one-third of the visitors of each month were reviewed. During the study period, 10,009 visited the travel clinic and a retrospective chart review was performed for 3,332 cases for analysis of travel patterns and prescriptions.

Results: People receiving yellow fever vaccine (YFV) (n = 2,933) were traveling more frequently for business and tourism and less frequently for providing non-medical service or research/education compared to the 399 people who did not receive the YFV. Overall, most people were traveling to Eastern Africa, South America, and Western Africa, while South-Eastern Asia was the most common destination for the non-YFV group. Besides YFV, the typhoid vaccine was the most commonly prescribed (54.2%), while hepatitis A presented the highest coverage (74.7%) considering the natural immunity, prior and current vaccination history. Additionally, 402 (82.5%) individuals received a prescription for MPM among the 487 individuals travelling to areas with high-risk of malaria infection. Age over 55 was independently associated with receiving MPM prescription, while purpose of providing service and travel duration over 10 days were associated with no MPM prescription, despite travelling to high-risk areas.

Conclusion: Eastern Africa and South America were common travel destinations among the visitors to a travel clinic for YFV, and most of them were travelling for tourism and business. For the individuals who are traveling to areas with high-risk for malaria, more proactive approach might be required in case of younger age travelers, longer duration, and travel purpose of providing service to minimize the risk of malaria infection.

Keywords: Antibiotic prophylaxis; Malaria; Travel medicine; Vaccine; Yellow fever.

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Figures

Figure 1
Figure 1. Selection of eligible cases for analysis on yellow fever vaccination and other prescriptions.
AT/PGU, atovaquone/proguanil; MQ, mefloquine; YFV, yellow fever vaccination; MPM, malaria prophylaxis medication.
Figure 2
Figure 2. Number of travelers by the visiting continents (A) Yellow fever vaccination group. (B) Non-yellow fever vaccination group. Continents with proportion of less than 1% were not visualized.
YFV, yellow fever vaccination.

References

    1. LaRocque RC, Rao SR, Lee J, Ansdell V, Yates JA, Schwartz BS, Knouse M, Cahill J, Hagmann S, Vinetz J, Connor BA, Goad JA, Oladele A, Alvarez S, Stauffer W, Walker P, Kozarsky P, Franco-Paredes C, Dismukes R, Rosen J, Hynes NA, Jacquerioz F, McLellan S, Hale D, Sofarelli T, Schoenfeld D, Marano N, Brunette G, Jentes ES, Yanni E, Sotir MJ, Ryan ET Global TravEpiNet Consortium. Global TravEpiNet: a national consortium of clinics providing care to international travelers--analysis of demographic characteristics, travel destinations, and pretravel healthcare of high-risk US international travelers, 2009-2011. Clin Infect Dis. 2012;54:455–462. - PubMed
    1. Freedman DO, Weld LH, Kozarsky PE, Fisk T, Robins R, von Sonnenburg F, Keystone JS, Pandey P, Cetron MS GeoSentinel Surveillance Network. Spectrum of disease and relation to place of exposure among ill returned travelers. N Engl J Med. 2006;354:119–130. - PubMed
    1. van Genderen PJ, van Thiel PP, Mulder PG, Overbosch D Dutch Schiphol Airport Study Group. Trends in knowledge, attitudes, and practices of travel risk groups toward prevention of hepatitis A: results from the Dutch Schiphol Airport survey 2002 to 2009. J Travel Med. 2012;19:35–43. - PubMed
    1. Lobel HO, Baker MA, Gras FA, Stennies GM, Meerburg P, Hiemstra E, Parise M, Odero M, Waiyaki P. Use of malaria prevention measures by North American and European travelers to East Africa. J Travel Med. 2001;8:167–172. - PubMed
    1. Zhang M, Liu Z, He H, Luo L, Wang S, Bu H, Zhou X. Knowledge, Attitudes, and Practices on Malaria Prevention Among Chinese International Travelers. J Travel Med. 2011;18:173–177. - PubMed