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. 1989 Mar 27;98(2):135-8.
doi: 10.1016/0304-3940(89)90498-9.

Cell type-specific distribution of cathepsin B and D immunoreactivity within the rabbit retina

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Cell type-specific distribution of cathepsin B and D immunoreactivity within the rabbit retina

H G Bernstein et al. Neurosci Lett. .

Abstract

The cellular localization of cathepsin B and D immunoreactivity was demonstrated at the light microscopic level in the retina of adult rabbits by use of the peroxidase-antiperoxidase technique. Antisera were raised against rat liver enzymes. Whereas cathepsin D immunoreactivity was confined to Müller (glial) cells, cathepsin B was demonstrated in some, but not all, neuronal cell types. It is proposed that the two enzymes might carry different functions within the neuronal versus glial compartment.

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