Microfluidics: The future of microdissection TESE?
- PMID: 27104311
- DOI: 10.3109/19396368.2016.1159748
Microfluidics: The future of microdissection TESE?
Abstract
Non-obstructive azoospermia (NOA) is a severe form of infertility accounting for 10% of infertile men. Microdissection testicular sperm extraction (microTESE) includes a set of clinical protocols from which viable sperm are collected from patients (suffering from NOA), for intracytoplasmic sperm injection (ICSI). Clinical protocols associated with the processing of a microTESE sample are inefficient and significantly reduce the success of obtaining a viable sperm population. In this review we highlight the sources of these inefficiencies and how these sources can possibly be removed by microfluidic technology and single-cell Raman spectroscopy.
Keywords: IVF; microTESE; microfluidics; sperm separation.
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