Guillain-Barré syndrome and cytomegalovirus infection during pregnancy

Abstract

Guillain-Barré syndrome (GBS) is an immune-mediated disorder which can be triggered by cytomegalovirus (CMV) infection. GBS following CMV primary infection is a rare event during pregnancy, which raises the question of maternal and fetal management. We describe an unusual case of GBS after CMV primary infection in a pregnant woman. The mother was successfully treated with standard immunoglobulins but in utero fetal death caused by CMV congenital infection unfortunately occurred. Similar cases have rarely been reported in the literature.

Keywords: Congenital infection; Cytomegalovirus; Guillain-Barré syndrome; Immunoglobulins; Pregnancy.