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Editorial
. 2016 Jul 17;15(14):1803-4.
doi: 10.1080/15384101.2016.1179037. Epub 2016 Apr 22.

PGK1 is a new member of the protein kinome

Xinjian Li  1 , Yanhua Zheng  1 , Zhimin Lu  1   2   3
Affiliations
Editorial

PGK1 is a new member of the protein kinome

Xinjian Li et al. Cell Cycle. .
No abstract available

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Figures

Figure 1.
Figure 1.
PGK1 and PKM2 possess dual glycolytic enzyme and protein kinase functions. PGK1 and PKM2 catalyze the 2 ATP-generating reactions in the glycolysis pathway. Mitochondrial PGK1 phosphorylates PDHK1 using ATP as a phosphate donor, and PKM2, but not PKM1, phosphorylates its protein substrates using PEP as a phosphate donor.
See this image and copyright information in PMC

Comment on

  • Feature to: Li X. et al. Mitochondria-translocated PGK1 functions as a protein kinase to coordinate glycolysis and the TCA cycle in tumorigenesis. Mol Cell 2016; 61(5):705-19; PMID:26942675; http://dx.doi.org/10.1016/j.molcel.2016.02.009

References

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