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Comment
. 2016 May 2;15(9):1180-1.
doi: 10.1080/15384101.2016.1154374. Epub 2016 Apr 25.

Driving WDR62 to the pole

Dan Xu  1   2 , Zhiheng Xu  1   3   4
Affiliations
Comment

Driving WDR62 to the pole

Dan Xu et al. Cell Cycle. .
No abstract available

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Figures

Figure 1.
Figure 1.
TPX2 regulates AURKA activity to control WDR62 localization. During M Phase, TPX2 activates AURKA. AURKA phosphorylates WDR62 and contributes to their co-localization at mitotic spindle. AURKA and JNK phosphorylate WDR62 in the N-terminal (red) and C-terminal (black) respectively. In TPX2 knockdown cells, AURKA activity decreases, leading to the failed recruitment of WDR62 to the spindle pole.
See this image and copyright information in PMC

Comment on

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