Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2016 Apr 22;14(4):76.
doi: 10.3390/md14040076.

Potential Pharmacological Resources: Natural Bioactive Compounds from Marine-Derived Fungi

Liming Jin  1 , Chunshan Quan  2 , Xiyan Hou  3 , Shengdi Fan  4
Affiliations
Review

Potential Pharmacological Resources: Natural Bioactive Compounds from Marine-Derived Fungi

Liming Jin et al. Mar Drugs. .

Abstract

In recent years, a considerable number of structurally unique metabolites with biological and pharmacological activities have been isolated from the marine-derived fungi, such as polyketides, alkaloids, peptides, lactones, terpenoids and steroids. Some of these compounds have anticancer, antibacterial, antifungal, antiviral, anti-inflammatory, antioxidant, antibiotic and cytotoxic properties. This review partially summarizes the new bioactive compounds from marine-derived fungi with classification according to the sources of fungi and their biological activities. Those fungi found from 2014 to the present are discussed.

Keywords: bioactive compounds; fungal metabolites; marine-derived fungi; natural products.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Structures of compounds 1–2.
Figure 2
Figure 2
Structures of compounds 3–9.
Figure 3
Figure 3
Structures of compounds 10–14.
Figure 4
Figure 4
Structures of compounds 15–18.
Figure 5
Figure 5
Structures of compounds 19–20.
Figure 6
Figure 6
Structures of compounds 21–24.
Figure 7
Figure 7
Structures of compounds 25–29.
Figure 8
Figure 8
Structures of compounds 30–31.
Figure 9
Figure 9
Structures of compounds 32–37.
Figure 10
Figure 10
Structures of compounds 38–40.
Figure 11
Figure 11
Structures of compounds 41–46.
Figure 12
Figure 12
Structures of compounds 47–52.
Figure 13
Figure 13
Structures of compounds 53–60.
Figure 14
Figure 14
Structures of compounds 61–66.
Figure 15
Figure 15
Structures of compounds 67–71.
Figure 16
Figure 16
Structures of compounds 72–75.
Figure 17
Figure 17
Structures of compounds 76–82.
Figure 18
Figure 18
Structures of compounds 83–85.
Figure 19
Figure 19
Structures of compounds 86–88.
Figure 20
Figure 20
Structures of compounds 89–91.
Figure 21
Figure 21
Structures of compounds 92–94.
Figure 22
Figure 22
Structures of compounds 95–98.
Figure 23
Figure 23
Structures of compounds 99–112.
Figure 24
Figure 24
Structures of compounds 113–116.
Figure 25
Figure 25
Structures of compounds 117–120.
Figure 26
Figure 26
Structures of compounds 121–126.
Figure 27
Figure 27
Structures of compounds 127–133.
Figure 28
Figure 28
Structures of compounds 134–136.
Figure 29
Figure 29
Structures of compounds 137–139.
Figure 30
Figure 30
Structures of compounds 140–142.
Figure 31
Figure 31
Structures of compounds 143–146.
Figure 32
Figure 32
Structures of compounds 147–149.
Figure 33
Figure 33
Structures of compounds 150–153.
Figure 34
Figure 34
New compounds from marine-derived fungi included in this review, divided by sources of the fungal strains.
Figure 35
Figure 35
New compounds from marine-derived fungi included in this review, divided by structural types.
Figure 36
Figure 36
Bioactive categories of new compounds from marine-derived fungi included in this review.
See this image and copyright information in PMC

References

    1. Schueffler A., Anke T. Fungal natural products in research and development. Nat. Prod. Rep. 2014;31:1425–1448. doi: 10.1039/C4NP00060A. - DOI - PubMed
    1. Rateb M.E., Ebel R. Secondary metabolites of fungi from marine habitats. Nat. Prod. Rep. 2011;28:290–344. doi: 10.1039/c0np00061b. - DOI - PubMed
    1. Blunt J.W., Copp B.R., Keyzers R.A., Munro M.H.G., Prinsep M.R. Marine natural products. Nat. Prod. Rep. 2015;32:116–211. doi: 10.1039/C4NP00144C. - DOI - PubMed
    1. Hamilton-Miller J.M.T. Development of the semi-synthetic penicillins and cephalosporins. Int. J. Antimicrob. Agents. 2008;31:189–192. doi: 10.1016/j.ijantimicag.2007.11.010. - DOI - PubMed
    1. Blunt J.W., Copp B.R., Munro M.H.G., Northcote P.T., Prinsep M.R. Marine natural products. Nat. Prod. Rep. 2011;28:196–268. doi: 10.1039/C005001F. - DOI - PubMed

Publication types

Substances

LinkOut - more resources