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Review
. 2016 Apr;5(2):159-75.
doi: 10.3978/j.issn.2304-3881.2015.10.04.

Living donor liver transplantation in Europe

Silvio Nadalin  1 , Ivan Capobianco  1 , Fabrizio Panaro  1 , Fabrizio Di Francesco  1 , Roberto Troisi  1 , Mauricio Sainz-Barriga  1 , Paolo Muiesan  1 , Alfred Königsrainer  1 , Giuliano Testa  1
Affiliations
Review

Living donor liver transplantation in Europe

Silvio Nadalin et al. Hepatobiliary Surg Nutr. 2016 Apr.

Abstract

Living donor liver transplantation (LDLT) sparked significant interest in Europe when the first reports of its success from USA and Asia were made public. Many transplant programs initiated LDLT and some of them especially in Germany and Belgium became a point of reference for many patients and important contributors to the advancement of the field. After the initial enthusiasm, most of the European programs stopped performing LDLT and today the overall European activity is concentrated in a few centers and the number of living donor liver transplants is only a single digit fraction of the overall number of liver transplants performed. In this paper we analyse the present European activities and highlight the European contribution to the advancement of the field of LDLT.

Keywords: Europe; Liver transplantation (LT); living donor; living donor liver transplantation (LDLT).

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Conflict of interest statement

Conflicts of Interest: The authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1
Annual rates of deceased donors pmp in Europe from 2005−2013 (1). pmp, per million people.
Figure 2
Figure 2
Chronological evolution of LDLT in Europe from 1991 to 2013 (5). LDLT, living donor liver transplantation.
Figure 3
Figure 3
Number of deceased donors per million population in Eurotransplant countries 2012 and 2013 (17).
Figure 4
Figure 4
Evolution of DDLT and LDLT in Eurotransplant Area between 1991 and 2013 (17). DDLT, deceased donor liver transplantation; LDLT, living donor liver transplantation.
Figure 5
Figure 5
Overall 1-, 3-, 5-year graft and recipient survival rates after DDLT (n=8,183) and LDLT (n=638) in ET during the observation period 2010−2014 (17). DDLT, deceased donor liver transplantation; LDLT, living donor liver transplantation.
Figure 6
Figure 6
Chronological evolution of LDLT (adult and paediatric) in Germany from 1991 to 2012 (17). LDLT, living donor liver transplantation.
Figure 7
Figure 7
LDLT activity in Belgium from between 2000 and 2010. LDLT, living donor liver transplantation.
Figure 8
Figure 8
LDLT activity in Italy between 2001 and 2013 (55). LDLT, living donor liver transplantation.
Figure 9
Figure 9
Distribution of LDLT activity in Italy according to recipient age between 2001 and 2013 (55). LDLT, living donor liver transplantation.
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References

    1. Spanisch National Transplant Organisation - Organización Nacional de Trasplantes. Annual rates of deceased donors pmp in Europe from 2005-2013. Available online: http://www.ont.es/infesp/Paginas/DatosdeDonacionyTrasplante.aspx
    1. Broelsch CE, Malago M, Testa G, et al. Living donor liver transplantation in adults: outcome in Europe. Liver Transpl 2000;6:S64-5. - PubMed
    1. Dutkowski P, De Rougemont O, Müllhaupt B, et al. Current and future trends in liver transplantation in Europe. Gastroenterology 2010;138:802-9.e1-4. - PubMed
    1. European Liver Transplant Registry. Documents to download. Available online: http://www.eltr.org/spip.php?page=documents
    1. Registry ELT. Evolution of LTs in Europe European Liver Transplant Registry. Available online: http://www.eltr.org/Evolution-of-LTs-in-Europe.html