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Comment
. 2016 Apr 27;18(5):465-6.
doi: 10.1038/ncb3352.

Fibroblasts form a hospitable metastatic niche in the liver

Neta Erez  1
Affiliations
Comment

Fibroblasts form a hospitable metastatic niche in the liver

Neta Erez. Nat Cell Biol. .

Abstract

The liver is the most common metastatic route of pancreatic cancer. Early recruitment of granulin-secreting inflammatory monocytes to the liver is now shown to reprogram hepatic stellate cells into myofibroblasts that modulate the liver microenvironment to support the growth of metastasizing tumour cells.

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References

    1. J Exp Med. 2014 Jul 28;211(8):1503-23 - PubMed
    1. J Pathol. 2013 Jan;229(2):198-207 - PubMed
    1. Nature. 2016 Feb 4;530(7588):42-3 - PubMed
    1. Cancer Res. 2013 Mar 15;73(6):1721-32 - PubMed
    1. Nature. 2011 Dec 07;481(7379):85-9 - PubMed

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