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. 2017 Apr 1;38(13):935-941.
doi: 10.1093/eurheartj/ehw145.

Targeting reperfusion injury in patients with ST-segment elevation myocardial infarction: trials and tribulations

Derek J Hausenloy  1   2   3   4 , Hans Erik Botker  5 , Thomas Engstrom  6 , David Erlinge  7 , Gerd Heusch  8 , Borja Ibanez  9   10 , Robert A Kloner  11   12 , Michel Ovize  13   14 , Derek M Yellon  3   4 , David Garcia-Dorado  15
Affiliations

Targeting reperfusion injury in patients with ST-segment elevation myocardial infarction: trials and tribulations

Derek J Hausenloy et al. Eur Heart J. .
No abstract available

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Figures

Figure 1
Figure 1
Main mechanisms of cardiomyocyte cell death during myocardial reperfusion and their inter-relations.
Figure 2
Figure 2
Various time-windows for applying therapeutic strategies for reducing myocardial infarct size in STEMI patients undergoing PPCI.
See this image and copyright information in PMC

References

    1. Cung TT, Morel O, Cayla G, Rioufol G, Garcia-Dorado D, Angoulvant D, Bonnefoy-Cudraz E, Guerin P, Elbaz M, Delarche N, Coste P, Vanzetto G, Metge M, Aupetit JF, Jouve B, Motreff P, Tron C, Labeque JN, Steg PG, Cottin Y, Range G, Clerc J, Claeys MJ, Coussement P, Prunier F, Moulin F, Roth O, Belle L, Dubois P, Barragan P, Gilard M, Piot C, Colin P, De PF, Morice MC, Ider O, Dubois-Rande JL, Unterseeh T, Le BH, Beard T, Blanchard D, Grollier G, Malquarti V, Staat P, Sudre A, Elmer E, Hansson MJ, Bergerot C, Boussaha I, Jossan C, Derumeaux G, Mewton N, Ovize M. Cyclosporine before PCI in patients with acute myocardial infarction. N Engl J Med 2015;373:1021–1031. - PubMed
    1. Campo G, Guastaroba P, Marzocchi A, Santarelli A, Varani E, Vignali L, Sangiorgio P, Tondi S, Serenelli C, De PR, Saia F. Impact of COPD on long-term outcome after ST-segment elevation myocardial infarction receiving primary percutaneous coronary intervention. Chest 2013;144:750–757. - PubMed
    1. Piper HM, Garcia-Dorado D, Ovize M. A fresh look at reperfusion injury. Cardiovasc Res 1998;38:291–300. - PubMed
    1. Yellon DM, Hausenloy DJ. Myocardial reperfusion injury. N Engl J Med 2007;357:1121–1135. - PubMed
    1. Heusch G. Cardioprotection: chances and challenges of its translation to the clinic. Lancet 2013;381:166–175. - PubMed

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