Acceptability and Feasibility of Sexually Transmitted Infection Testing and Treatment among Pregnant Women in Gaborone, Botswana, 2015

doi:10.1155/2016/1251238

. 2016:2016:1251238.

doi: 10.1155/2016/1251238. Epub 2016 Mar 28.

Acceptability and Feasibility of Sexually Transmitted Infection Testing and Treatment among Pregnant Women in Gaborone, Botswana, 2015

Adriane Wynn¹, Doreen Ramogola-Masire², Ponatshego Gaolebale³, Neo Moshashane⁴, Ogechukwu Agatha Offorjebe⁵, Kaitlin Arena⁶, Jeffrey D Klausner⁷, Chelsea Morroni⁸

Affiliations

¹ Department of Health Policy and Management, Fielding School of Public Health, University of California, Los Angeles, 650 Charles Young Dr. S., 31-269 CHS, P.O. Box 951772, Los Angeles, CA 90095-1772, USA.
² Botswana-UPenn Partnership, 244G UB Main Campus, Gaborone, Botswana; University of Botswana, 4775 Notwane Road, Gaborone, Botswana.
³ Princess Marina Hospital, Phologolo Extension 9, Gaborone, Botswana.
⁴ University of Botswana, 4775 Notwane Road, Gaborone, Botswana.
⁵ Charles R. Drew University of Medicine & Science, 1731 E. 120th Street, Los Angeles, CA 90059, USA; David Geffen School of Medicine, University of California, Los Angeles, 10833 Le Conte Avenue, Los Angeles, CA 90095, USA.
⁶ David Geffen School of Medicine, University of California, Los Angeles, 10833 Le Conte Avenue, Los Angeles, CA 90095, USA.
⁷ Division of Infectious Diseases, Department of Epidemiology, David Geffen School of Medicine and Fielding School of Public Health, University of California, Los Angeles, 10833 Le Conte Avenue, CHS 13-154a, Los Angeles, CA 90095, USA.
⁸ Botswana-UPenn Partnership, 244G UB Main Campus, Gaborone, Botswana; EGA Institute for Women's Health and Institute for Global Health, University College London, 74 Huntley Street, London WC1E 6AU, UK; Wits Reproductive Health and HIV Institute, University of Witwatersrand, 58 Klein Street, Johannesburg 2001, South Africa.

PMID: 27119076
PMCID: PMC4826911
DOI: 10.1155/2016/1251238

Acceptability and Feasibility of Sexually Transmitted Infection Testing and Treatment among Pregnant Women in Gaborone, Botswana, 2015

Adriane Wynn et al. Biomed Res Int. 2016.

. 2016:2016:1251238.

doi: 10.1155/2016/1251238. Epub 2016 Mar 28.

Authors

Adriane Wynn¹, Doreen Ramogola-Masire², Ponatshego Gaolebale³, Neo Moshashane⁴, Ogechukwu Agatha Offorjebe⁵, Kaitlin Arena⁶, Jeffrey D Klausner⁷, Chelsea Morroni⁸

Affiliations

¹ Department of Health Policy and Management, Fielding School of Public Health, University of California, Los Angeles, 650 Charles Young Dr. S., 31-269 CHS, P.O. Box 951772, Los Angeles, CA 90095-1772, USA.
² Botswana-UPenn Partnership, 244G UB Main Campus, Gaborone, Botswana; University of Botswana, 4775 Notwane Road, Gaborone, Botswana.
³ Princess Marina Hospital, Phologolo Extension 9, Gaborone, Botswana.
⁴ University of Botswana, 4775 Notwane Road, Gaborone, Botswana.
⁵ Charles R. Drew University of Medicine & Science, 1731 E. 120th Street, Los Angeles, CA 90059, USA; David Geffen School of Medicine, University of California, Los Angeles, 10833 Le Conte Avenue, Los Angeles, CA 90095, USA.
⁶ David Geffen School of Medicine, University of California, Los Angeles, 10833 Le Conte Avenue, Los Angeles, CA 90095, USA.
⁷ Division of Infectious Diseases, Department of Epidemiology, David Geffen School of Medicine and Fielding School of Public Health, University of California, Los Angeles, 10833 Le Conte Avenue, CHS 13-154a, Los Angeles, CA 90095, USA.
⁸ Botswana-UPenn Partnership, 244G UB Main Campus, Gaborone, Botswana; EGA Institute for Women's Health and Institute for Global Health, University College London, 74 Huntley Street, London WC1E 6AU, UK; Wits Reproductive Health and HIV Institute, University of Witwatersrand, 58 Klein Street, Johannesburg 2001, South Africa.

PMID: 27119076
PMCID: PMC4826911
DOI: 10.1155/2016/1251238

Abstract

Introduction: Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), and Trichomonas vaginalis (TV) are curable sexually transmitted infections (STIs) that can cause adverse maternal and birth outcomes. Most countries do not conduct routine testing during antenatal care. We present data on the acceptability and feasibility of testing and treating pregnant women for STIs in an antenatal clinic in Gaborone, Botswana.

Materials and methods: We offered CT, NG, and TV testing using self-collected vaginal swabs to eligible pregnant women. Participants received same-day test results. Those who tested positive were given treatment.

Results: Among the 225 women who were eligible and recruited, 200 (89%) agreed to participate. The median age of our study sample was 30 years; most were unmarried (77%), with a median gestational age of 27 weeks and a 23% HIV prevalence. All participants received their results with at least 72% (n = 143) on the same day. Thirty participants (15%) tested positive for an STI, all were treated, and 24 (80%) were treated on the same day.

Conclusion: The acceptability of STI testing was high, and the intervention was feasible. This study provides support for continued research into STI prevalence, cost-effectiveness, and the association of STIs with adverse maternal and infant outcomes.

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Figures

**Figure 2**
Number of patients eligible, recruited, and enrolled by week in the Chlamydia trachomatis, *Neisseria gonorrhoeae*, and Trichomonas vaginalis study in Gaborone, Botswana, 2015.

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References

1. World Health Organization. Global Incidence and Prevalence of Selected Curable Sexually Transmitted Infections—2008. Geneva, Switzerland: World Health Organization; 2012.
1. Institute of Medicine. Preterm Birth: Causes, Consequences, and Prevention. Committee on Understanding Premature Birth and Assuring Healthy Outcomes; 2007.
1. Silveira M. F., Ghanem K. G., Erbelding E. J., et al. Chlamydia trachomatis infection during pregnancy and the risk of preterm birth: a case-control study. International Journal of STD and AIDS. 2009;20(7):465–469. doi: 10.1258/ijsa.2008.008388. - DOI - PubMed
1. Claman P., Toye B., Peeling R. W., Jessamine P., Belcher J. Serologic evidence of Chlamydia trachomatis infection and risk of preterm birth. Canadian Medical Association Journal. 1995;153(3):259–262. - PMC - PubMed
1. Gencay M., Koskiniemi M., Ämmälä P., et al. Chlamydia trachomatis seropositivity is associated both with stillbirth and preterm delivery. APMIS. 2000;108(9):584–588. doi: 10.1034/j.1600-0463.2000.d01-101.x. - DOI - PubMed

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[1] World Health Organization. Global Incidence and Prevalence of Selected Curable Sexually Transmitted Infections—2008. Geneva, Switzerland: World Health Organization; 2012.

[2] World Health Organization. Global Incidence and Prevalence of Selected Curable Sexually Transmitted Infections—2008. Geneva, Switzerland: World Health Organization; 2012.

[3] Institute of Medicine. Preterm Birth: Causes, Consequences, and Prevention. Committee on Understanding Premature Birth and Assuring Healthy Outcomes; 2007.

[4] Institute of Medicine. Preterm Birth: Causes, Consequences, and Prevention. Committee on Understanding Premature Birth and Assuring Healthy Outcomes; 2007.

[5] Silveira M. F., Ghanem K. G., Erbelding E. J., et al. Chlamydia trachomatis infection during pregnancy and the risk of preterm birth: a case-control study. International Journal of STD and AIDS. 2009;20(7):465–469. doi: 10.1258/ijsa.2008.008388. - DOI - PubMed

[6] Silveira M. F., Ghanem K. G., Erbelding E. J., et al. Chlamydia trachomatis infection during pregnancy and the risk of preterm birth: a case-control study. International Journal of STD and AIDS. 2009;20(7):465–469. doi: 10.1258/ijsa.2008.008388. - DOI - PubMed

[7] Claman P., Toye B., Peeling R. W., Jessamine P., Belcher J. Serologic evidence of Chlamydia trachomatis infection and risk of preterm birth. Canadian Medical Association Journal. 1995;153(3):259–262. - PMC - PubMed

[8] Claman P., Toye B., Peeling R. W., Jessamine P., Belcher J. Serologic evidence of Chlamydia trachomatis infection and risk of preterm birth. Canadian Medical Association Journal. 1995;153(3):259–262. - PMC - PubMed

[9] Gencay M., Koskiniemi M., Ämmälä P., et al. Chlamydia trachomatis seropositivity is associated both with stillbirth and preterm delivery. APMIS. 2000;108(9):584–588. doi: 10.1034/j.1600-0463.2000.d01-101.x. - DOI - PubMed

[10] Gencay M., Koskiniemi M., Ämmälä P., et al. Chlamydia trachomatis seropositivity is associated both with stillbirth and preterm delivery. APMIS. 2000;108(9):584–588. doi: 10.1034/j.1600-0463.2000.d01-101.x. - DOI - PubMed

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Acceptability and Feasibility of Sexually Transmitted Infection Testing and Treatment among Pregnant Women in Gaborone, Botswana, 2015

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Acceptability and Feasibility of Sexually Transmitted Infection Testing and Treatment among Pregnant Women in Gaborone, Botswana, 2015

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