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Review
. 2016:2016:4864195.
doi: 10.1155/2016/4864195. Epub 2016 Mar 29.

Apical External Root Resorption and Repair in Orthodontic Tooth Movement: Biological Events

Liviu Feller  1 , Razia A G Khammissa  1 , George Thomadakis  2 , Jeanine Fourie  1 , Johan Lemmer  1
Affiliations
Review

Apical External Root Resorption and Repair in Orthodontic Tooth Movement: Biological Events

Liviu Feller et al. Biomed Res Int. 2016.

Abstract

Some degree of external root resorption is a frequent, unpredictable, and unavoidable consequence of orthodontic tooth movement mediated by odontoclasts/cementoclasts originating from circulating precursor cells in the periodontal ligament. Its pathogenesis involves mechanical forces initiating complex interactions between signalling pathways activated by various biological agents. Resorption of cementum is regulated by mechanisms similar to those controlling osteoclastogenesis and bone resorption. Following root resorption there is repair by cellular cementum, but factors mediating the transition from resorption to repair are not clear. In this paper we review some of the biological events associated with orthodontically induced external root resorption.

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References

    1. Brezniak N., Wasserstein A. Orthodontically induced inflammatory root resorption. Part II: the clinical aspects. Angle Orthodontist. 2002;72(2):180–184. - PubMed
    1. Castro I., Valladares-Neto J., Estrela C. Contribution of cone beam computed tomography to the detection of apical root resorption after orthodontic treatment in root-filled and vital teeth. Angle Orthodontist. 2015;85(5):771–776. doi: 10.2319/042814-308.17. - DOI - PMC - PubMed
    1. Roscoe M. G., Meira J. B. C., Cattaneo P. M. Association of orthodontic force system and root resorption: a systematic review. American Journal of Orthodontics and Dentofacial Orthopedics. 2015;147(5):610–626. doi: 10.1016/j.ajodo.2014.12.026. - DOI - PubMed
    1. Sharab L. Y., Morford L. A., Dempsey J., et al. Genetic and treatment-related risk factors associated with external apical root resorption (EARR) concurrent with orthodontia. Orthodontics and Craniofacial Research. 2015;18(1):71–82. doi: 10.1111/ocr.12078. - DOI - PMC - PubMed
    1. Mauès C. P. R., do Nascimento R. R., Vilella O. D. V. Severe root resorption resulting from orthodontic treatment: prevalence and risk factors. Dental Press Journal of Orthodontics. 2015;20(1):52–58. doi: 10.1590/2176-9451.20.1.052-058.oar. - DOI - PMC - PubMed

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