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Comment
. 2016 Apr 27;48(5):478-9.
doi: 10.1038/ng.3554.

Fat eggs shape offspring health

Erica D Watson  1 , Joanna Rakoczy  1
Affiliations
Comment

Fat eggs shape offspring health

Erica D Watson et al. Nat Genet. .

Abstract

How maternal diet influences offspring metabolism is unclear, as it is difficult to distinguish between the effects of the in utero environment and epigenetic factors contributed by the oocyte. In a mouse model of high-fat diet, a new study teases apart these mechanisms by using in vitro fertilization and shows that susceptibility of offspring to metabolic disorder can likely be attributed to epigenetic inheritance via the oocyte.

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References

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