Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2016 May 19;374(20):1996-8.
doi: 10.1056/NEJMc1509501. Epub 2016 Apr 27.

Visual Acuity after Retinal Gene Therapy for Choroideremia

Thomas L Edwards  1 , Jasleen K Jolly  1 , Markus Groppe  1 , Alun R Barnard  1 , Charles L Cottriall  2 , Tanya Tolmachova  3 , Graeme C Black  4 , Andrew R Webster  5 , Andrew J Lotery  6 , Graham E Holder  5 , Kanmin Xue  1 , Susan M Downes  1 , Matthew P Simunovic  1 , Miguel C Seabra  3 , Robert E MacLaren  7
Affiliations
Case Reports

Visual Acuity after Retinal Gene Therapy for Choroideremia

Thomas L Edwards et al. N Engl J Med. .
No abstract available

PubMed Disclaimer

References

    1. Jacobson SG, Cideciyan AV, Roman AJ, et al. Improvement and decline in vision with gene therapy in childhood blindness. N Engl J Med. 2015;372:1920–6. - PMC - PubMed
    1. Bainbridge JWB, Mehat MS, Sundaram V, et al. Long-term effect of gene therapy on Leber’s congenital amaurosis. N Engl J Med. 2015;372:1887–97. - PMC - PubMed
    1. MacLaren RE, Groppe M, Barnard AR, et al. Retinal gene therapy in patients with choroideremia: initial findings from a phase 1/2 clinical trial. Lancet. 2014;383:1129–37. - PMC - PubMed