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. 1989 Apr;40(4):377-83.
doi: 10.4269/ajtmh.1989.40.377.

A specific diagnostic antigen of Echinococcus granulosus with an apparent molecular weight of 8 kDA

S E Maddison  1 , S B Slemenda, P M Schantz, J A Fried, M Wilson, V C Tsang
Affiliations

A specific diagnostic antigen of Echinococcus granulosus with an apparent molecular weight of 8 kDA

S E Maddison et al. Am J Trop Med Hyg. 1989 Apr.

Abstract

An echinococcus antigen with an apparent molecular weight of 8 kDa was identified as diagnostically important. An immunoblot assay using this antigen was 91% sensitive for surgically confirmed Echinococcus granulosus hydatid disease of the liver. Specificity was 100% for echinococcosis. Marked cross-reactivity was observed with serum specimens from patients with E. multilocularis and E. vogeli infections. The 8 kDa component was not related to the widely recognized echinococcus antigen 5.

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