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Review
. 2015 Nov;31(6):500-6.
doi: 10.6515/acs20150319b.

Preconception Counseling for Women with Congenital Heart Disease

Affiliations
Review

Preconception Counseling for Women with Congenital Heart Disease

Chun-Wei Lu et al. Acta Cardiol Sin. 2015 Nov.

Abstract

With advances that have been made over the recent decades in transcatheter and surgical interventions, most patients with congenital heart disease (CHD) can survive into adulthood. Overall, probably half of these surviving patients are female. When these female CHD patients reach childbearing age, however, pregnancy management will be a major issue. In order to meet the demands of fetal growth, the maternal cardiovascular system starts a series of adaptations beginning in early pregnancy. These adaptations include: decreased systemic and pulmonary vascular resistances, decreased blood pressure, expansion of the blood volume, increased heart rate and increased cardiac output. For women with CHD, this hemodynamic alteration may increase the risks of adverse cardiovascular events as well as the fetal and neonatal complications. Therefore, proper risk stratification and effective counseling for women with CHD who are planning their pregnancies is an important undertaking.

Key words: Congenital heart disease; Pregnancy.

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Figures

Figure 1
Figure 1
The flowchart for preconception assessment and counseling for women with congenital heart disease. CPX, cardiopulmonary exercise test; PE, physical examinations; WHO, World Health Organization.

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References

    1. Warnes CA, Liberthson R, Danielson GK, et al. Task force 1: the changing profile of congenital heart disease in adult life. J Am Coll Cardiol. 2001;37:1170–1175. - PubMed
    1. Marelli AJ, Mackie AS, Ionescu-Ittu R, et al. Congenital heart disease in the general population: changing prevalence and age distribution. Circulation. 2007;115:163–172. - PubMed
    1. Khairy P, Ouyang DW, Fernandes SM, et al. Pregnancy outcomes in women with congenital heart disease. Circulation. 2006:517–524. - PubMed
    1. Drenthen W, Pieper PG, Roos-Hesselink JW, et al. Outcome of pregnancy in women with congenital heart disease, a literature review. J Am Coll Cardiol. 2007;49:2303–2311. - PubMed
    1. Drenthen W, Boersma E, Balci A, et al. Predictors of pregnancy complications in women with congenital heart disease. Eur Heart J. 2010;31:2124–2132. - PubMed

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