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. 2016 Apr 21;21(16).
doi: 10.2807/1560-7917.ES.2016.21.16.30203.

High specificity of a novel Zika virus ELISA in European patients after exposure to different flaviviruses

Daniela Huzly  1 , Ingeborg Hanselmann, Jonas Schmidt-Chanasit, Marcus Panning
Affiliations
Free article

High specificity of a novel Zika virus ELISA in European patients after exposure to different flaviviruses

Daniela Huzly et al. Euro Surveill. .
Free article

Abstract

The current Zika virus (ZIKV) epidemic in the Americas caused an increase in diagnostic requests in European countries. Here we demonstrate high specificity of the Euroimmun anti-ZIKV IgG and IgM ELISA tests using putative cross-reacting sera of European patients with antibodies against tick-borne encephalitis virus, dengue virus, yellow fever virus and hepatitis C virus. This test may aid in counselling European travellers returning from regions where ZIKV is endemic.

Keywords: ELISA; European travellers; Zika virus; cross-reactivity; flavivirus; specificity.

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