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. 2016 Dec 1:22 Suppl 5:S120-S124.
doi: 10.1016/j.cmi.2015.12.005. Epub 2016 Apr 26.

Universal influenza vaccines: a realistic option?

R D de Vries  1 , A F Altenburg  1 , G F Rimmelzwaan  2
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Free article

Universal influenza vaccines: a realistic option?

R D de Vries et al. Clin Microbiol Infect. .
Free article

Abstract

The extensive antigenic drift displayed by seasonal influenza viruses and the risk of pandemics caused by newly emerging antigenically distinct influenza A viruses of novel subtypes has raised considerable interest in the development of so-called universal influenza vaccines. We review options for the development of universal flu vaccines and discuss progress that has been made recently.

Keywords: Antibodies; Immunity; Influenza; T lymphocytes; Universal vaccine; Virus vectors.

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