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Case Reports
. 2016 Jan-Mar;7(1):38-40.
doi: 10.4103/0976-7800.179176.

Zidovudine-induced nail hyper-pigmentation in 45-year-old women prescribed for HIV/tuberculosis co-infection

Vishal R Tandon  1 , Shamiya Sadiq  2 , Vijay Khajuria  2 , Annil Mahajan  3 , Sudhaa Sharma  4 , Zahid Gillani  2
Affiliations
Case Reports

Zidovudine-induced nail hyper-pigmentation in 45-year-old women prescribed for HIV/tuberculosis co-infection

Vishal R Tandon et al. J Midlife Health. 2016 Jan-Mar.

Abstract

Zidovudine is an important component of first-line antiretroviral treatment regimens used to manage HIV and tuberculosis (TB) co-infection. Nail pigmentation is documented both in adult as well as pediatric HIV patients, but to the best of our knowledge, it has not been reported in 45-year-old women of HIV/TB co-infection. Such an adverse drugs reactions (ADR), although is harmless and reversible, psychological aspects of such ADR may be immense to the extent that it can negatively affect the compliance and result in therapeutic failure. Thus, it is worth reporting.

Keywords: Adverse drugs reactions; HIV and tuberculosis co-infection; Zidovudine; nail hyper-pigmentation.

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Figure 1
Figure 1
Showing nail hyper pigmentation in advancing age female patient due to zidovudine
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