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Review
. 2016 Aug:40:139-148.
doi: 10.1016/j.copbio.2016.04.005. Epub 2016 Apr 29.

Synthetic biology-application-oriented cell engineering

Mingqi Xie  1 , Viktor Haellman  1 , Martin Fussenegger  2
Affiliations
Review

Synthetic biology-application-oriented cell engineering

Mingqi Xie et al. Curr Opin Biotechnol. 2016 Aug.

Abstract

Synthetic biology applies engineering principles to biological systems and reprograms living cells to perform novel and improved functions. In this review, we first provide an update of common tools and design principles that enable user-defined control of mammalian cell activities with spatiotemporal precision. Next, we demonstrate some examples of how engineered mammalian cells can be developed towards biomedical solutions in the context of real-world problems.

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