Recent advances in CRISPR/Cas9 technology for targeting latent HIV-1 reservoirs
- PMID: 27139312
- DOI: 10.1097/QAD.0000000000001138
Recent advances in CRISPR/Cas9 technology for targeting latent HIV-1 reservoirs
Comment on
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CRISPR/gRNA-directed synergistic activation mediator (SAM) induces specific, persistent and robust reactivation of the HIV-1 latent reservoirs.Sci Rep. 2015 Nov 5;5:16277. doi: 10.1038/srep16277. Sci Rep. 2015. PMID: 26538064 Free PMC article.
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Specific Reactivation of Latent HIV-1 by dCas9-SunTag-VP64-mediated Guide RNA Targeting the HIV-1 Promoter.Mol Ther. 2016 Mar;24(3):508-21. doi: 10.1038/mt.2016.7. Epub 2016 Jan 18. Mol Ther. 2016. PMID: 26775808 Free PMC article.
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CRISPR-Cas9 Can Inhibit HIV-1 Replication but NHEJ Repair Facilitates Virus Escape.Mol Ther. 2016 Mar;24(3):522-6. doi: 10.1038/mt.2016.24. Epub 2016 Jan 22. Mol Ther. 2016. PMID: 26796669 Free PMC article.
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