Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2016 Jul;36(4):375-6.
doi: 10.3343/alm.2016.36.4.375.

Hemoglobin Camperdown [β104Arg→Ser] Detection During Hemoglobin A(1c) Measurement via Capillary Electrophoresis

Valéry Brunel  1 , Patrick Caneiro  2 , Agnès Lahary  3 , Guy Hue  4 , Christian Thuillez  4   5
Affiliations
Case Reports

Hemoglobin Camperdown [β104Arg→Ser] Detection During Hemoglobin A(1c) Measurement via Capillary Electrophoresis

Valéry Brunel et al. Ann Lab Med. 2016 Jul.
No abstract available

PubMed Disclaimer

Conflict of interest statement

Authors' Disclosures of Potential Conflicts of Interest: No potential conflicts of interest relevant to this article were reported.

Figures

Fig. 1
Fig. 1. Abnormal electropherogram obtained by Capillarys 2 Flex Piercing instrument. Abnormal electropherogram with software alarm "atypical profile" showing a peak of unknown hemoglobin (HbCa1c), which is the glycated form of hemoglobin Camperdown (HbCa). HbCa is not visible owing to co-eluation with HbA0.
See this image and copyright information in PMC

References

    1. Jaisson S, Leroy N, Meurice J, Guillard E, Gillery P. First evaluation of Capillarys 2 Flex Piercing® (Sebia) as a new analyzer for HbA1c assay by capillary electrophoresis. Clin Chem Lab Med. 2012;50:1769–1775. - PubMed
    1. Weykamp C, Kemna E, Leppink S, Siebelder C. Glycation rate of haemoglobins S, C, D, E, J and G, and analytical interference on the measurement of HbA1c with affinity chromatography and capillary electrophoresis. Clin Chem Lab Med. 2015;53:e207–e210. - PubMed
    1. Ji L, Yu J, Zhou Y, Xia Y, Xu A, Li W, et al. Erroneous HbA1c measurements in the presence of β-thalassemia and common Chinese hemoglobin variants. Clin Chem Lab Med. 2015;53:1451–1458. - PubMed
    1. Wilkinson T, Gough P, Owen MC, Carrell RW, Kronenberg H. Detection of variants of haemoglobin D in Australia: haemoglobin D Camperdown alpha 2 A beta 2 121 Glu leads to Val and haemoglobin D Punjab alpha 2 A beta 2 121 Glu leads to Gin. Med J Aust. 1974;26:636–637. - PubMed
    1. Gaborit B, Nicolay A, Valéro R, Bégu A, Badens C, Bellanné-Chantelot C, et al. Comparison of performances of various HbA1c methods in Haemoglobin Camperdown variant detection: consequences in diabetes management. Clin Chim Acta. 2009;403:262–263. - PubMed

Publication types

LinkOut - more resources