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. 2016 Oct;52(5):732-7.
doi: 10.1007/s11262-016-1348-4. Epub 2016 May 3.

Isolation and molecular characterization of reassortant H11N3 subtype avian influenza viruses isolated from domestic ducks in Zhejiang Province in China

Haibo Wu  1 , Xiuming Peng  2 , Xiaorong Peng  2 , Nanping Wu  3
Affiliations

Isolation and molecular characterization of reassortant H11N3 subtype avian influenza viruses isolated from domestic ducks in Zhejiang Province in China

Haibo Wu et al. Virus Genes. 2016 Oct.

Abstract

In July 2013, six H11N3 subtype avian influenza viruses (AIVs) were isolated from domestic ducks in Zhejiang Province in Eastern China. These strains were characterized by whole genome sequencing with subsequent phylogenetic analysis and genetic comparison. Phylogenetic analysis of all eight viral genes showed that these strains clustered in the AIV Eurasian lineage, and these strains received their genes from H11, H7, and H1 AIVs in Eastern China. These strains were found to be minimally pathogenic in mice, and were able to replicate in mice without prior adaptation. Continued surveillance is needed considering the important role of domestic ducks in AIV reassortment.

Keywords: Avian influenza viruses; Domestic ducks; Reassortment; Subtype H11N3.

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