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. 2016 May 3;11(1):75.
doi: 10.1186/s13019-016-0459-2.

Does sinus rhythm conversion after cardiac surgery affect postoperative health- related quality of life?

Henrica N A M van Breugel  1 , Orlando Parise  1 , Fred H M Nieman  2 , Ryan E Accord  1 , Fabiana Lucà  1 , Pieter Lozekoot  1 , Narendra Kumar  1 , Ghislaine A P G van Mastrigt  1 , Jan F M A Nijs  1 , Ries Vrakking  3 , Jos G Maessen  1 , Mark La Meir  1 , Sandro Gelsomino  4   5
Affiliations

Does sinus rhythm conversion after cardiac surgery affect postoperative health- related quality of life?

Henrica N A M van Breugel et al. J Cardiothorac Surg. .

Abstract

Background: We investigated the impact and the predictive value of sinus rhythm at 12 months (SR12) on subscales of three different HrQoL questionnaires: SF-36., EuroQoL and MFI 20.

Methods: Data of 125 cardiac surgery patients with pre-operative AF from our previous randomized trial were used. Based on their rhythm outcome patients were divided in two groups: SR12 or AF at 12 months follow up (non-SR12). All questionnaires were self-administered pre-operatively and at 3 months, 6 months and 12 months after surgery.

Results: Synus rhytm at 12 months was predictive of improvement of SF36- mental score (MS, p = 0.021), Euro-QoL-MS (p = 0.009), VAS (p = 0.006), and MFI 20-MS (p = 0.009). We failed to find any significant interactions between SR12 and any of the other significant risk factors: age <65 years, paroxysmal type of AF and preoperative AF duration <12 months. In contrast, SR12 was not significant in predicting physical score (PS) subscales of any of the questionnaires (all, p > 0.05) which were predicted by age <65 years (SF36-PS, p = 0.029) by paroxysmal type of AF and age <65 years (Euro-QoL-PS, p = 0.017 and p = 0.04, respectively) and by AF duration <12 months, paroxysmal type of AF and age < 65 years (MFI 20-PS, p = 0.019, p = 0.020 and p = 0.015, respectively).

Conclusions: Specific mental-related HrQoL scales are much more sensitive to sinus rhythm conversion. Sinus rithm mantainance shows significant effects on mental scores independently of other cofactors. Successful conversion to sinus rhythm after surgical ablation during cardiac surgery does not significantly affect phisical health related quality of life during 1 year follow up.

Keywords: Ablation; Atrial fibrillation; Health related quality of life.

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Figures

Fig. 1
Fig. 1
SF-36 subscales in patients with or without recurrent arrhythmia at 12 month-follow-up. * Significance between follow-up steps.≠ Inter-group significance significance
Fig. 2
Fig. 2
SF-36 subscales Composite Scores. in patients with or without recurrent arrhythmia at 12 month-follow-up. * Significance between follow-up steps.≠ Inter-group significance significance
Fig. 3
Fig. 3
EQ-5D sub-domains and VAS score in patients with or without recurrent arrhythmia at 12 month-follow-up. * Significance between follow-up steps.≠ Inter-group significance significance
Fig. 4
Fig. 4
MFI-20 sub-domains in patients with or without recurrent arrhythmia at 12 month-follow-up. * Significance between follow-up steps.≠ Inter-group significance significance
Fig. 5
Fig. 5
Sub-analysis analysis of effect of SR12 on HrQoL- questionnaires by co-factors
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