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Case Reports
. 2016 Mar 24:18:22-3.
doi: 10.1016/j.rmcr.2016.03.007. eCollection 2016.

Tracheo-parenchymal fistula following concurrent chemo-radiation for stage III NSCLC

Bashar Alzghoul  1 , Nikhil Meena  2
Affiliations
Case Reports

Tracheo-parenchymal fistula following concurrent chemo-radiation for stage III NSCLC

Bashar Alzghoul et al. Respir Med Case Rep. .

Abstract

Non-Small Cell Cancer (NSCLC) are frequently diagnosed at a later stage [1]. Treatment involves chemotherapy and radiation, either sequentially or concurrently [2]. Concurrent therapy is more efficacious but also associated with more complications [4-6]. We present a rare care of trachea-pulmonary fistula formation after concurrent chemo and radiation in a patient with Squamous Cell Cancer (SCC).

Keywords: Bronchoscopy; Chemo-radiation; Lung cancer; Tracheo-pulmonary fistula.

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Figures

Fig. 1
Fig. 1
Computed tomography scan of the chest showing a 3.2 × 3.3 cm hilar mass with endo-bronchial extension, narrowing the right main bronchus (A). Computed tomography scan of the chest showing a thick walled cavity in the right upper lobe with tracheo-parenchymal fistula just above the right upper lobe bronchus (B). Bronchoscopy revealed a tracheoparenchymal fistula connecting the right main bronchus to a large cavity in the right upper lobe, destroying majority of the right main bronchus and causing significant attenuation of the bronchus intermedius (C).
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References

    1. Price A. Emerging developments of chemoradiotherapy in stage III NSCLC. Nat. Rev. Clin. Oncol. 2012;9:591–598. - PubMed
    1. Detterbeck F.C., Lewis S.Z., Diekemper R. Executive summary: diagnosis and management of lung cancer, 3rd ed: American college of chest physicians evidence-based clinical practice guidelines. CHEST J. 2013;143(Suppl. 5):7S–37S. - PubMed
    1. Aupérin A., Le Péchoux C., Rolland E. Meta-analysis of concomitant versus sequential radiochemotherapy in locally advanced non-small-cell lung cancer. J. Clin. Oncol. 2010;28:2181–2190. - PubMed
    1. Jalal S.I., Riggs H.D., Melnyk A. Updated survival and outcomes for older adults with inoperable stage III non-small-cell lung cancer treated with cisplatin, etoposide, and concurrent chest radiation with or without consolidation docetaxel: analysis of a phase III trial from the Hoosier O. Ann. Oncol. 2012;23(7):1730–1738. - PubMed
    1. Lee C.B., Stinchcombe T.E., Moore D.T. Late complications of high-dose (>/=66 Gy) thoracic conformal radiation therapy in combined modality trials in unresectable stage III non-small cell lung cancer. J. Thorac. Oncol. 2009;4:74–79. - PubMed

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