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Review
. 2016 Jul;55(7):952-5.
doi: 10.1007/s00120-016-0089-2.

[Side effect management of tyrosine kinase inhibitors in urology : Hypertension]

[Article in German]
D Sikic  1 , N Meidenbauer  2 , V Lieb  1 , B Keck  3
Affiliations
Review

[Side effect management of tyrosine kinase inhibitors in urology : Hypertension]

[Article in German]
D Sikic et al. Urologe A. 2016 Jul.

Abstract

Tyrosine kinase inhibitors like sunitinib, sorafenib, pazopanib or axintinib are regarded the standard of care in the systemic therapy of metastatic renal cell carcinoma. However, the many side effects associated with this therapy pose challenges for the treating physician and the patient. This review offers an overview of the classification and the treatment of hypertension, which is one of the major side effects induced by all tyrosine kinase inhibitors, in order to improve treatment efficacy and patient compliance.

Keywords: Axitinib; Cabozantinib; Pazopanib; Sorafenib; Sunitinib.

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