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Review
. 2015 Sep 28:7:69-77.
doi: 10.2147/OAEM.S71279. eCollection 2015.

Targeted temperature management in emergency medicine: current perspectives

Benton R Hunter  1 , Timothy J Ellender  2
Affiliations
Review

Targeted temperature management in emergency medicine: current perspectives

Benton R Hunter et al. Open Access Emerg Med. .

Abstract

Landmark trials in 2002 showed that therapeutic hypothermia (TH) after out-of-hospital cardiac arrest due to ventricular tachycardia or ventricular fibrillation resulted in improved likelihood of good neurologic recovery compared to standard care without TH. Since that time, TH has been frequently instituted in a wide range of cardiac arrest patients regardless of initial heart rhythm. Recent evidence has evaluated how, when, and to what degree TH should be instituted in cardiac arrest victims. We outline early evidence, as well as recent trials, regarding the use of TH or targeted temperature management in these patients. We also provide evidence-based suggestions for the institution of targeted temperature management/TH in a variety of emergency medicine settings.

Keywords: cardiac arrest; heart arrest; therapeutic hypothermia.

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Figures

Figure 1
Figure 1
Targeted temperature management (TTM). Abbreviations: SpO2, peripheral capillary oxygen saturation; ETCO2, end-tidal carbon dioxide; pCO2, partial pressure of carbon dioxide; SBP, systolic blood pressure; MAP, mean arterial pressure; EKG, electrocardiogram; STEMI, ST-elevation myocardial infarction; PCI, percutaneous coronary intervention; GCS, Glasgow Coma Score; IV, intravenous.
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