Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2016 Apr 22:4:20.
doi: 10.3389/fchem.2016.00020. eCollection 2016.

Whither Enzymology in the Twenty First Century?

E N G Marsh  1
Affiliations

Whither Enzymology in the Twenty First Century?

E N G Marsh. Front Chem. .
No abstract available

Keywords: computational modeling; enzyme design; enzyme mechanisms; microbiome; radical SAM enzymes.

PubMed Disclaimer

References

    1. Albery W. J., Knowles J. R. (1976). Evolution of enzyme function and development of catalytic activity. Biochemistry 15, 5631–5640. 10.1021/bi00670a032 - DOI - PubMed
    1. Blake C. C. F., Koenig D. F., Mair G. A., North A. C. T., Phillips D. C., Sarma V. R. (1965). Structure of hen egg-white lysozyme – a 3-dimensional fourier synthesis at 2 Å resolution. Nature 206, 757–761. 10.1038/206757a0 - DOI - PubMed
    1. Blomberg R., Kries H., Pinkas D. M., Mittl P. R. E., Gruetter M. G., Privett H. K., et al. . (2013). Precision is essential for efficient catalysis in an evolved Kemp eliminase. Nature 503, 418–421. 10.1038/nature12623 - DOI - PubMed
    1. Chien A., Edgar D. B., Trela J. M. (1976). Deoxyribonucleic acid polymerase from extreme thermophile Thermus aquaticus. J. Bacteriol. 127, 1550–1557. - PMC - PubMed
    1. Chirpich T. P., Zappia V., Costilow R. N., Barker H. A. (1970). Lysine 2,3-aminomutase – purification and properties of a pyridoxal phosphate and S-adenosylmethionine activated enzyme. J. Biol. Chem. 245, 1778–1789. - PubMed

LinkOut - more resources