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Comment
. 2016 May 5;12(5):e1005979.
doi: 10.1371/journal.pgen.1005979. eCollection 2016 May.

Spermatogenesis Studies Reveal a Distinct Nonsense-Mediated mRNA Decay (NMD) Mechanism for mRNAs with Long 3'UTRs

Oliver Mühlemann  1
Affiliations
Comment

Spermatogenesis Studies Reveal a Distinct Nonsense-Mediated mRNA Decay (NMD) Mechanism for mRNAs with Long 3'UTRs

Oliver Mühlemann. PLoS Genet. .
No abstract available

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Conflict of interest statement

The author has declared that no competing interests exist.

Figures

Fig 1
Fig 1. Illustration depicting mammalian spermatogenesis and the effect of a UPF2 or TDRD6 knockout on two different types of NMD-targeted mRNAs.
Precursors of chromatid bodies (CBs: red) begin to form in late-stage spermatocytes at the end of meiosis and condense into the typical CB structure in early round spermatids. CBs are enriched in different classes of RNA, NMD factors, and additional proteins, including TDRD6 and MHV.
See this image and copyright information in PMC

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