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. 2016 Aug;101(8):e336-8.
doi: 10.3324/haematol.2016.143768. Epub 2016 May 5.

C-MYC is related to GATA3 expression and associated with poor prognosis in nodal peripheral T-cell lymphomas

Rebeca Manso  1 , Carmen Bellas  2 , Paloma Martín-Acosta  2 , Manuela Mollejo  3 , Javier Menárguez  4 , Federico Rojo  1 , Pilar Llamas  5 , Miguel A Piris  6 , Socorro M Rodríguez-Pinilla  7
Affiliations

C-MYC is related to GATA3 expression and associated with poor prognosis in nodal peripheral T-cell lymphomas

Rebeca Manso et al. Haematologica. 2016 Aug.
No abstract available

Keywords: C-MYC; GATA3; PTCL.

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Figures

Figure 1.
Figure 1.
Kaplan–Meier survival curves of biological marker expression in the complete series (A) of n-PTCL patients and in the AITL (B) and PTCL-NOS (C) histological subgroups.
Figure 2.
Figure 2.
Kaplan–Meier survival curves of C-MYC expression in the AITL subgroup of patients in the low-risk and high-risk PIT subgroups.
See this image and copyright information in PMC

References

    1. Iqbal J, Wright G, Wang C, et al. Gene expression signatures delineate biological and prognostic subgroups in peripheral T-cell lymphoma. Blood. 2014;123(19):2915–2923. - PMC - PubMed
    1. Wang X, Werneck MB, Wilson BG, et al. TCR-dependent transformation of mature memory phenotype T cells in mice. J Clin Invest. 2011;121(10):3834–3845. - PMC - PubMed
    1. Rodriguez-Pinilla SM, Sanchez ME, Rodriguez J, et al. Loss of TCR-beta F1 and/or EZRIN expression is associated with unfavorable prognosis in nodal peripheral T-cell lymphomas. Blood Cancer J. 2013;3:e111. - PMC - PubMed
    1. Wang T, Feldman AL, Wada DA, et al. GATA-3 expression identifies a high-risk subset of PTCL, NOS with distinct molecular and clinical features. Blood. 2014;123(19):3007–3015. - PMC - PubMed
    1. Yan ZX, Wu LL, Xue K, et al. MicroRNA187 overexpression is related to tumor progression and determines sensitivity to bortezomib in peripheral T-cell lymphoma. Leukemia. 2014;28(4):880–887. - PubMed

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