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. 2016 May 5;165(4):773-5.
doi: 10.1016/j.cell.2016.04.057.

Thoughts on Obesity and Brain Glucose

Michael T Heneka  1 , Pierluigi Nicotera  2
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Thoughts on Obesity and Brain Glucose

Michael T Heneka et al. Cell. .
Free article

Abstract

Homeostatic control of brain metabolism is essential for neuronal activity. Jais et al., (2016) report that reduced brain glucose uptake elicited by a high-fat diet self-corrects by the recruitment of peripheral, VEGF-producing macrophages to the blood-brain barrier. Their findings further suggest that restoring brain glucose availability might help protect from cognitive impairment in Alzheimer's disease.

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