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Review
. 2017 Feb;186(1):57-62.
doi: 10.1007/s11845-016-1464-0. Epub 2016 May 7.

From inflammation to cancer

A Korniluk  1 , O Koper  1 , H Kemona  1 , V Dymicka-Piekarska  2
Affiliations
Review

From inflammation to cancer

A Korniluk et al. Ir J Med Sci. 2017 Feb.

Abstract

Background: The participation of inflammation in the progression of cancer for many years have been the subject of research.

Methods: In the 19th century, there was evidence that an acute inflammation may inhibit the development of cancer. However, chronic inflammation affects the progression of the disease.

Results: Today, it is known that inflammation and cancer use similar mechanisms of development such as severe cell proliferation or angiogenesis. It has been shown that prolonged presence of inflammatory cells and factors in the tumor microenvironment can accelerate its growth and inhibit apoptosis of transformed cells.

Conclusion: In this article we present a brief history of the discovery mechanisms and potential links between acute and chronic inflammation and cancer.

Keywords: Acute inflammation; Adhesion molecules; Cancer; Chronic inflammation.

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Conflict of interest statement

Conflict of interest

The authors have no conflicts of interest to disclose.

Ethical approval

This article does not contain any studies with human participants or animals performed by any of the authors.

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