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Review
. 2016 May 6;7(2):227-34.
doi: 10.4292/wjgpt.v7.i2.227.

Update on management of Barrett's esophagus

Affiliations
Review

Update on management of Barrett's esophagus

Fernando Macías-García et al. World J Gastrointest Pharmacol Ther. .

Abstract

Barrett's esophagus (BE) is a common condition that develops as a consequence of gastroesophageal reflux disease. The significance of Barrett's metaplasia is that predisposes to cancer development. This article provides a current evidence-based review for the management of BE and related early neoplasia. Controversial issues that impact the management of patients with BE, including definition, screening, clinical aspects, diagnosis, surveillance, and management of dysplasia and early cancer have been assessed.

Keywords: Barrett metaplasia; Barrett’s esophagus; Esophageal adenocarcinoma; Gastroesophageal reflux disease; Radiofrequency ablation.

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Figures

Figure 1
Figure 1
Algorithm for the screening, surveillance and management of Barrett's esophagus. GERD: Gastroesophageal reflux disease; BMI: Body mass index. BE: Barrett's esophagus.
Figure 2
Figure 2
Management of high-grade dysplasia and early cancer in Barrett's esophagus. RFA: Radiofrequency ablation; BE: Barrett's esophagus; HGD: High-grade dysplasia; EC: Early cancer; EA: Esophageal adenocarcinoma.

References

    1. Barrett NR. Chronic peptic ulcer of the oesophagus and “oesophagitis”. Br J Surg. 1950;38:175–182. - PubMed
    1. Spechler SJ, Sharma P, Souza RF, Inadomi JM, Shaheen NJ. American Gastroenterological Association medical position statement on the management of Barrett’s esophagus. Gastroenterology. 2011;140:1084–1091. - PubMed
    1. Fitzgerald RC, di Pietro M, Ragunath K, Ang Y, Kang JY, Watson P, Trudgill N, Patel P, Kaye PV, Sanders S, et al. British Society of Gastroenterology guidelines on the diagnosis and management of Barrett’s oesophagus. Gut. 2014;63:7–42. - PubMed
    1. Riddell RH, Odze RD. Definition of Barrett’s esophagus: time for a rethink--is intestinal metaplasia dead? Am J Gastroenterol. 2009;104:2588–2594. - PubMed
    1. Ronkainen J, Aro P, Storskrubb T, Johansson SE, Lind T, Bolling-Sternevald E, Vieth M, Stolte M, Talley NJ, Agréus L. Prevalence of Barrett’s esophagus in the general population: an endoscopic study. Gastroenterology. 2005;129:1825–1831. - PubMed

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