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. 2016 Aug;37(6):1119-22.
doi: 10.1007/s00246-016-1403-x. Epub 2016 May 9.

An Observation from Liver Biopsies Two Decades Post-Fontan

William N Evans  1   2 , Ruben J Acherman  3   4 , Leigh C Reardon  3   5 , Alvaro Galindo  3   4 , Abraham Rothman  3   4 , Michael L Ciccolo  3   4 , Sergio A Carrillo  3   4 , Brody J Winn  6 , Noel S Yumiaco  6 , Humberto Restrepo  3   4
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An Observation from Liver Biopsies Two Decades Post-Fontan

William N Evans et al. Pediatr Cardiol. 2016 Aug.

Abstract

This brief report describes an observation from liver biopsy results in nonfailing Fontan patients, currently in their second postoperative decade. In three patients, with either atriopulmonary or atrioventricular connections and functional left ventricles, we found no portal fibrosis. In contrast, we found portal fibrosis in three clinically similar, nonfailing Fontan patients with lateral tunnel connections and functional left ventricles. We recognize the results may be secondary to chance; nevertheless, we speculate about possible relevancy.

Keywords: Congenital heart disease; Fontan operation; Liver biopsy; Liver fibrosis.

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