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. 2016 Aug;32(8):583-585.
doi: 10.1016/j.pt.2016.04.016. Epub 2016 May 5.

Tuft Cells: A New Flavor in Innate Epithelial Immunity

Richard K Grencis  1 , John J Worthington  2
Affiliations
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Tuft Cells: A New Flavor in Innate Epithelial Immunity

Richard K Grencis et al. Trends Parasitol. 2016 Aug.

Abstract

How host cells sense intestinal parasitic infection and initiate the appropriate immune response has long been a focus of many immunologists. Three new papers now identify a critical role for tuft cells, an epithelial cell type involved in perception of taste, as key players that kick-start type 2 immunity.

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